In reverse gear

Myosin shifts into reverse gear.

213 news & views time to useful timescales. By manipulating the ratio of these modified monomers, Rant and co-workers created nanopores that contained only a single nitrilotriacetic acid group within the sensing zone of the nanopore, which could be used to detect the reversible binding of single proteins. In another part of the study, Rant and colleagues functionalized a nanopore with three nit...

Hunt for the Primary—A Diagnostic Drive in Reverse Gear!!!

Skeletal metastasis from primary hepatocellular carcinoma is rare ranging from 03 to 20% and is mostly seen in autopsy cases. Patients presenting with symptoms of bone metastasis are still rarer. Only a few cases of metastasis to bone from hepatocellular carcinoma have been reported as per literature review. Other cancers like breast, prostate, and lung carcinomas show an increased incidence of...

Learning in High Gear:

Building on the literature of dynamic capability and organizational learning, we examine strategy execution in hyper-competition as a problem of how organizations can re-configure their learning capability to match with their radically different learning demands. Organizations in hyper-competitive environments face an increasing gap between their learning opportunities and needs, and actual lea...

Savery, N. (2014). A reverse gear for transcription-coupled DNA repair?

Gear Optimization

In this study, an optimization methodology is presented to systematically define head-cutter geometry and machine tool settings to introduce optimal tooth modifications in spiral bevel and hypoid gears. The goal of the optimization is to simultaneously minimize the tooth contact pressure and the angular displacement error of the driven gear (the transmission error), to maximize the elastohydrod...